BREAKING: Huge Fireball Erupts After UPS Plane Crashes Near Louisville Airport – Three Crew Members Feared Dead (VIDEO)

A UPS plane with three crew members onboard crashed on takeoff from the Louisville, Kentucky, airport on Tuesday evening.

Per CNN: “A UPS MD-11 plane crashed near the Louisville, Kentucky, airport, according to preliminary information, a source says.”

“The Federal Aviation Administration said the plane crashed at about 5:15 p.m. It was taking off for Honolulu,” the AP reported.

Video posted to X showed a massive fireball the moment the plane crashed.

Aerial video of the aftermath of the plane crash shows a massive fire burning.

#BREAKING: Aerial shot of the huge fire after plane crashes in Louisville, Kentucky pic.twitter.com/RCPN1Ruied

— Rapid Report (@RapidReport2025) November 4, 2025

Multiple people are injured. It is unclear if there are any fatalities.

CBS News reported:

Injuries have been reported after a UPS plane crashed near the Louisville International Airport on Tuesday, according to police.

The Louisville Metro Police Department described the scene as active with “fire and debris,” warning residents to stay away from Fern Valley and Grade Lane, an intersection located on the south side of the airport, which serves as the hub of UPS.

A shelter-in-place has been issued for a 5-mile radius of the airport, police said.

UPS said in a statement that it was notified of an incident involving one of its aircraft, but didn’t immediately provide more details.

WATCH LIVE: We have a camera outside Louisville Airport in Kentucky, where a cargo plane has reportedly crashed. https://t.co/MDZFHSx03c

— Off The Press (@OffThePress1) November 4, 2025

Transportation Secretary Sean Duffy provided an update:

– UPS cargo flight 2976
– Crashed around 5:15 ET after takeoff from Louisville Muhammad Ali International Airport en route to Honolulu
– The aircraft was a McDonnell Douglas MD-11.

Heartbreaking images coming out of Kentucky tonight.

Here’s an update from @FAANews
– UPS cargo flight 2976
– Crashed around 5:15 ET after takeoff from Louisville Muhammad Ali International Airport en route to Honolulu
– The aircraft was a McDonnell Douglas MD-11.

Please… pic.twitter.com/yE1Brhv8cQ

— Secretary Sean Duffy (@SecDuffy) November 4, 2025

BREAKING…please check back for updates.

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